Magnetic resonance imaging (MRI) data from 25 patients before and after tumor resection surgery can be accessed on the EBRAINS Knowledge Graph.

EBRAINS has provided scientists with the tools to address one of neuroscience's oldest enigmas: the dichotomy of brain function and structure.

Researchers are using The Virtual Brain - an open-source platform for constructing and simulating personalised brain network models on EBRAINS - to simulate the effects of deep brain stimulation in Parkinson's disease. Their results have been published in Experimental Neurology.

The EBRAINS-supported PHRASE project aims to deliver a platform for prognosis and intervention protocols for AI-based rehabilitation. The platform will inform clinicians to make better treatment decisions through an AI-enhanced, cloud-based, and VR-delivered intervention.

Research is being conducted using brain simulations, patient-specific models, and predictive software to improve the success rate of epilepsy surgery. Epilepsy was once considered unfathomably complex: through collaborative effort, digital simulation, and clinical application, we are instead seeing it with new eyes.

A new co-simulation interface will link molecular chemical signaling to whole-brain network dynamics, allowing researchers to study complex multiscale interactions involved in brain diseases such as Alzheimer’s. The new interface will be available on EBRAINS in early 2023.

Researchers have discovered four new brain regions in the human anterior prefrontal cortex that are crucial to cognitive functioning. The newly identified areas in females are larger than those in males in two cases. Using the new probabilistic maps, scientists were able to directly correlate the structure and function of the areas by superimposing datasets from functional studies. These maps are being integrated into the EBRAINS Julich Brain Atlas.

The team analysed in detail which parts of the brain changed over time using the Julich Brain Atlas on EBRAINS. The findings suggest that the volumes of certain brain regions decrease over time in a specific pattern that is associated with clinical symptoms and largely coincides with the pattern described in Braak’s famous staging theory.

The study demonstrates a method to unravel structure-function relationships by using the multilevel Julich-Brain Atlas on EBRAINS to bridge the different scales of brain organisation. The findings provide insight into the visual, auditory, somatosensory, and motor systems of the brain.