Mice have taken a prominent role as experimental animals in neuroscience over the last two decades. The most widely used, openly shared atlas for the mouse brain is the Allen Mouse Brain Atlas. EBRAINS is using the Allen Mouse Brain Coordinate Framework (CCFv3) as a basis for combining and comparing data from mouse brains. The atlas is embedded in our interactive atlas viewer, as well as in spatially-focused workflows and several other EBRAINS tools for analysing data from the mouse brain.
EBRAINS utilises the Allen Mouse Brain Common Coordinate Framework (CCFv3) to compare, analyse and showcase neuroscience data from the mouse brain. The CCFv3 is defined in a population-averaged image volume, acquired from 1,675 male C57BL/6J mice using serial two-photon tomography (STPT). The most recent version of the CCFv3 (CCFv3-2017) contains more than 600 brain regions delineated in 3D based on this template. Atlas files and the technical information needed to download and use the Allen Mouse Brain Common Coordinate Framework are available from the Allen Institute web portal.