fastPLI

The Fiber Architecture Simulation Toolbox for PLI (fastpli) is a toolbox for polarized light imaging (PLI) with three main purposes:

  • Sandbox - designing of nerve fiber models: The first module allows the user to create different types of nerve fiber bundles and additionally fill them with individual nerve fibers.

  • Solver - generating collision free models: The second module takes as input a configuration of nerve fibers and checks them for spatial collisions. Since nerve fibers cannot overlap in reality, one must ensure that the models follow the same rules. The solver module implements a simple algorithm that checks for collisions and, if it finds any, pushes the colliding segments of the fibers slightly apart. This is repeated until all collisions are solved.

  • Simulation - simulation of 3D-Polarized Light Imaging: The simulation module enables the simulation of 3D Polarized Light Imaging (3D-PLI). This is a microscopic technique that allows the polarization change of light moving through a brain section to be measured. Due to the birefringence property of the myelin surrounding the nerve fibers, the polarization state changes. This change enables the calculation of the 3d orientation of the nerve fibers in the brain slice.

Launch online
Contributors
FM

Other Tools

See all tools

siibra-explorer

siibra-explorer is built around an interactive 3D view of the brain displaying a unique selection of detailed templates and parcellation maps for the human, macaque, rat or mouse brain, including BigBrain as a microscopic resolution human brain model at its full resolution of 20 micrometres.

Collaboratory

The EBRAINS Collaboratory offers researchers and developers a secure environment to work with others. You control the level of collaboration by sharing your projects with specific users, teams or all of the Internet. Many researchers are sharing their work already; several services, tools, datasets and other resources are publicly available, and many more are available for registered users.

MeshView

MeshView is a web application for real-time 3D display of surface mesh data representing structural parcellations from volumetric atlases, such as the Waxholm Space Atlas of the Sprague Dawley Rat Brain. MeshView is available as an EBRAINS community app, accessible via a collab (further info: https://wiki.ebrains.eu/bin/view/Collabs/image-registration-and-analysis-demo/) Key features: orbiting view with toggleable opaque/transparent/hidden parcellation meshes rendering user defined cut surface as if meshes were solid objects rendering point-clouds (simple type-in, or loaded from a JSON format) coordinate system is compatible with QuickNII (https://www.nitrc.org/projects/quicknii)

Create an account

EBRAINS is open and free. Sign up now for complete access to our tools and services.

Register