Ratioscope

Genetically-encoded biosensors are heavily used in biology to monitor biological processes in real time within living cells. Many of such biosensors use two different emission wavelengths that change in opposite directions: the biological signal is measured as a change in the ratio of these two emissions. This so-called ratiometric quantification is standard and applies to many situations. Ratioscope, which runs in the Igor Pro environment, offers two packages:

  • Ratio analysis of fluorescence images: image corrections, display in pseudocolor, measurements, kymograph, analysis of periodic activity, movies...
  • Fusion module: statistics on series of experiments, to compare different experimental conditions; generate editor-ready graphs and plots.
Launch online
Source Code
Contributors
PV

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