The Allen mouse brain atlas is a comprehensive digital resource that provides detailed information on the structure and function of the mouse brain. A wide range of structural and functional experimental data mapped to the Allen mouse brain atlas are shared via the EBRAINS research infrastructure.
EBRAINS utilises the Allen Mouse Brain Common Coordinate Framework (CCFv3) to compare, analyse and showcase neuroscience data from the mouse brain. The CCFv3 is defined in a population-averaged image volume, acquired from 1,675 male C57BL/6J mice using serial two-photon tomography (STPT).
The most recent version of the CCFv3 (CCFv3-2017) contains more than 600 brain regions delineated in 3D based on this template.
Atlas files and the technical information needed to download and use the Allen Mouse Brain Common Coordinate Framework are available from the Allen Brain Map Portal.
Allen Mouse Brain Common Coordinate Framework in the EBRAINS interactive atlas viewer
ExploreAllen Mouse Brain Atlas CCFv3 original publication
Read hereAllen Mouse Brain Atlas CCFv3 technical white paper
DownloadThe Allen Mouse Brain Common Coordinate Framework is the backbone of spatially-focused workflows and tools that support spatial registration of new data to the atlas framework, semi-automatic analyses using the brain region hierarchy and delineations, and visualisation of extracted data in 3D.
The atlas is incorporated in the QuickNII tool for spatial registration of serial 2D images, and employed in the QUINT workflow for extracting and quantifying labelled objects from images registered to the atlas.
siibra-explorer is built around an interactive 3D view of the brain displaying a unique selection of detailed templates and parcellation maps for the human, macaque, rat or mouse brain, including BigBrain as a microscopic resolution human brain model at its full resolution of 20 micrometres.
siibra-api is an HTTP API for querying and retrieving contents of EBRAINS atlases. Originally built as a backend service for the interactive atlas viewer siibra-explorer, the API has been documented for connecting the brain atlases to other applications and web services.
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